Make sure you have the latest drivers from the actual manufacturer's website, not whatever Windows Update gives you. Video card drivers especially — nVidia and ATI release new ones every month and they make a real difference.

Definitely back up your important files before trying any fixes. I learned this the hard way when I lost 3 years of photos trying to fix a simple problem. Get an external hard drive or burn DVDs of your important stuff first.

Honestly at some point a clean reinstall of Windows fixes more than any amount of tinkering. XP gets crufty after a couple years. Back up your files, find your product key, and do a fresh install. It'll feel like a brand new machine.

Check how much free space is on your hard drive. Windows needs at least 15% free to run well — it uses that space for virtual memory and the swap file. If your drive is 95% full, that alone will make everything crawl.

I always tell people: buy a UPS battery backup. A $40 one will protect your PC from power surges and brownouts that slowly kill your hardware. Lost a motherboard to a thunderstorm once. Never again.